Alcohol
You can drink alcohol while taking procyclidine, but it may make you sleepy and make you fall over. If you drink a lot alcohol, these effects will be more serious.
Drinking a lot of alcohol can also make the symptoms of your condition worse.
It might be best to stop drinking alcohol for a few days when you start taking procyclidine until you know how the medicine affects you.
If you want to drink alcohol while on procyclidine, remember that it may make you sleepy, so make sure you can get home safely.
Street drugs
Procyclidine does not mix well with street drugs.
Cannabis and procyclidine taken together increases your heart rate and may also make any drowsiness worse.
Amfetamine and procyclidine taken together increases your heart rate.
Methadone can make the more common side effects of procyclidine (such as dry mouth, blurred vision and constipation) worse.
If you are taking procyclidine to help treat the side effects of an antipsychotic medication, it is important to look up how your antipsychotic medication interacts with other drugs.
Procyclidine on its own can, in large doses, cause a high and make psychosis symptoms worse. Do not share your procyclidine with anyone else.
Smoking
Cigarette smoke does not affect the amount of procyclidine in your body, so you shouldn't have to change your dose of procyclidine if you start or stop smoking while on it.